Journal article

Inhibition of the pore-forming protein perforin by a series of aryl-substituted isobenzofuran-1(3H)-ones

Julie A Spicer, Kristiina M Huttunen, Christian K Miller, William A Denny, Annette Ciccone, Kylie A Browne, Joseph A Trapani

Bioorganic & Medicinal Chemistry | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2012

Grants

Awarded by Wellcome Trust


Awarded by Academy of Finland


Funding Acknowledgements

This work was supported by the Wellcome Trust (Grant 092717) and the Auckland Division of the Cancer Society of New Zealand. K. M. H. thanks the Academy of Finland (Grant 135439), the Finnish Cultural Foundation, and Jenny and Antti Wihuri Foundation for financial support. We also thank Sisira Kumara and Karin Tan for HPLC studies, and Maruta Boyd and Shannon Black for NMR studies.