Inhibition of the pore-forming protein perforin by a series of aryl-substituted isobenzofuran-1(3H)-ones
Julie A Spicer, Kristiina M Huttunen, Christian K Miller, William A Denny, Annette Ciccone, Kylie A Browne, Joseph A Trapani
Bioorganic & Medicinal Chemistry | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2012
Awarded by Wellcome Trust
Awarded by Academy of Finland
This work was supported by the Wellcome Trust (Grant 092717) and the Auckland Division of the Cancer Society of New Zealand. K. M. H. thanks the Academy of Finland (Grant 135439), the Finnish Cultural Foundation, and Jenny and Antti Wihuri Foundation for financial support. We also thank Sisira Kumara and Karin Tan for HPLC studies, and Maruta Boyd and Shannon Black for NMR studies.