Journal article
Rapid diagnostic test-based management of malaria: An effectiveness study in Papua New Guinean infants with plasmodium falciparum and plasmodium vivax malaria
N Senn, P Rarau, D Manong, M Salib, P Siba, LJ Robinson, J Reeder, S Rogerson, I Mueller, B Genton
Clinical Infectious Diseases | Published : 2012
DOI: 10.1093/cid/cir901
Abstract
Background. In malaria-endemic areas it is recommended that febrile children be tested for malaria by rapid diagnostic test (RDT) or blood slide (BS) and receive effective malaria treatment only if results are positive. However, RDTs are known to perform less well for Plasmodium vivax. We evaluated the safety of withholding antimalarial drugs from young Papua New Guinean children with negative RDT results in areas with high levels of both Plasmodium falciparum and P. vivax infections. Methods. longitudinal prospective study of children aged 3-27 months visiting outpatient clinics for fever. RDT was administered at first visit. RDT and microscopy were performed if children returned because of..
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Awarded by Bill and Melinda Gates Foundation
Funding Acknowledgements
This work was performed using data collected through an IPTi randomized controlled trial supported by a grant to the PNG IMR from the Bill & Melinda Gates Foundation's Global Health Program (grant number 34678).