PIDDosome-independent tumor suppression by Caspase-2
C Manzl, L Peintner, G Krumschnabel, F Bock, V Labi, M Drach, A Newbold, R Johnstone, Andreas Villunger
Cell Death & Differentiation | NATURE PUBLISHING GROUP | Published : 2012
Awarded by Austrian Science Fund (FWF)
Awarded by AICR
We thank K Rossi and B Rieder for animal husbandry; C Soratroi, R Pfeilschifter, I Gaggl and I Brosch for excellent technical assistance; P Lukas and his team (LINAC1-4) for enabling irradiation of mice (Center of Nuclear Medicine and Radiotherapy, University Medical Center of Innsbruck); G Bock for cell sorting; G Baier and N Herman-Kleiter for help with Bioplex analysis; D Vaux for Casp2<SUP>-/-</SUP> and M Serrano for p53<SUP>-/-</SUP> mice. This study was funded by the Austrian Science Fund (FWF; Y212-B12; SFB021), AICR project 06-440 to AV and the FP06 RTN 'ApopTrain' to AV and FB as well as the Daniel Swarovski Fond (DSF) and the Tyrolean Science Fund (TWF) to CM and the Austrian Krebshilfe-Tirol (CM and GK). RWJ is a Principal Research Fellow of the National Health and Medical Research Council of Australia (NHMRC) and supported by NHMRC Program and Project Grants, the Susan G Komen Breast Cancer Foundation, the Prostate Cancer Foundation of Australia, Cancer Council Victoria, The Leukemia Foundation of Australia, Victorian Breast Cancer Research Consortium, Victorian Cancer Agency and the Australian Rotary Health Foundation.