Acute kidney injury
Rinaldo Bellomo, John A Kellum, Claudio Ronco
LANCET | ELSEVIER SCIENCE INC | Published : 2012
Acute kidney injury (formerly known as acute renal failure) is a syndrome characterised by the rapid loss of the kidney's excretory function and is typically diagnosed by the accumulation of end products of nitrogen metabolism (urea and creatinine) or decreased urine output, or both. It is the clinical manifestation of several disorders that affect the kidney acutely. Acute kidney injury is common in hospital patients and very common in critically ill patients. In these patients, it is most often secondary to extrarenal events. How such events cause acute kidney injury is controversial. No specific therapies have emerged that can attenuate acute kidney injury or expedite recovery; thus, trea..View full abstract
RB and CR have received consultancy and speaking fees from Alere, Abbott Diagnostics, Gambro, Fresenius, B Braun, and Edwards Lifesciences. JAK has received consultancy and speaking fees from Alere, Abbott Diagnostics, Gambro, Baxter, and Fresenius.