The Anti-Cancer IgM Monoclonal Antibody PAT-SM6 Binds with High Avidity to the Unfolded Protein Response Regulator GRP78

Zachary Rosenes; Terrence D Mulhern; Danny M Hatters; Leodevico L Ilag; Barbara E Power; Chris Hosking; Frank Hensel; Geoffrey J Howlett; Yee-Foong Mok

Journal article

The Anti-Cancer IgM Monoclonal Antibody PAT-SM6 Binds with High Avidity to the Unfolded Protein Response Regulator GRP78

Zachary Rosenes, Terrence D Mulhern, Danny M Hatters, Leodevico L Ilag, Barbara E Power, Chris Hosking, Frank Hensel, Geoffrey J Howlett, Yee-Foong Mok

PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2012

DOI: 10.1371/journal.pone.0044927

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University of Melbourne Researchers

Terry Mulhern Author Biochemistry and Pharmacology

Yee-Foong Mok Author Bio21 Institute

Danny Hatters Author Biochemistry and Pharmacology

Geoff Howlett Author Biochemistry and Pharmacology

Related Projects (1)

Biophysical identification of natural human antibody targets

A natural human antibody, PAT-SM6, isolated using technology developed by the partner organisation (Patrys), offers promise as a therapy to ..

Grants

Awarded by Australian Research Council

Funding Acknowledgements

This research was supported by the Australian Research Council (LP100100392) with additional support provided by Patrys Ltd. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.