Regulation of Drosophila mesoderm migration by phosphoinositides and the PH domain of the Rho GTP exchange factor Pebble

Grants

Funding Acknowledgements

We thank J. Wang and A. Srivastava for help with the EP screen and A. Wilkes, U. Wiedemann and N. Lorensuhewa for assistance in cloning. We thank L. Cooley and L. Jones for fly lines and the pUB-2-GFP-PH<SUP>PLC partial derivative</SUP> plasmid. We thank J. Milverton for transgenic injections. We thank B. Edgar, H. Bellen, H. Richardson and the Bloomington stock centre for fly stocks. Antibodies were kindly provided by M. Leptin, D. Kiehart, H. Bellen, S. Roth and the Developmental Studies Hybridoma Bank. This work was supported by a RESTRACOMP scholarship from The Hospital for Sick Children (to J. T.), an operating grant from The Cancer Research Society, Inc. (to J. A. B.); the ARC Special Research Centre for the Molecular Genetics of Development. NHMRC project grant 316959 (to M.J.M. and R.S) and ARC Discovery Grant DP0987338 (to R.S.); S.J.F. acknowledges support from NIH New Innovator Award DP2OD004265 and R01CA138676. M.M.N. acknowledges support from the American Cancer Society.