Cannabis use and age at onset of symptoms in subjects at clinical high risk for psychosis.
S Dragt, DH Nieman, F Schultze-Lutter, F van der Meer, H Becker, L de Haan, PM Dingemans, M Birchwood, P Patterson, RKR Salokangas, M Heinimaa, A Heinz, G Juckel, H Graf von Reventlow, P French, H Stevens, S Ruhrmann, J Klosterkötter, DH Linszen, undefined EPOS group
Acta Psychiatrica Scandinavica | Wiley | Published : 2012
OBJECTIVE: Numerous studies have found a robust association between cannabis use and the onset of psychosis. Nevertheless, the relationship between cannabis use and the onset of early (or, in retrospect, prodromal) symptoms of psychosis remains unclear. The study focused on investigating the relationship between cannabis use and early and high-risk symptoms in subjects at clinical high risk for psychosis. METHOD: Prospective multicenter, naturalistic field study with an 18-month follow-up period in 245 help-seeking individuals clinically at high risk. The Composite International Diagnostic Interview was used to assess their cannabis use. Age at onset of high risk or certain early symptoms wa..View full abstract