An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copper(II)
Paul S Donnelly, Jeffrey R Liddell, SinChun Lim, Brett M Paterson, Michael A Cater, Maria S Savva, Alexandra I Mot, Janine L James, Ian A Trounce, Anthony R White, Peter J Crouch
Proceedings of the National Academy of Sciences of the United States of America | NATL ACAD SCIENCES | Published : 2012
The metal-responsive element-luciferase and Renillaluciferase constructs were kindly provided by Dr. Leo Klomp, Department of Metabolic and Endocrine Diseases, University Medical Center Utrecht, The Netherlands. The research was supported by funds from the Australian National Health and Medical Research Council and the Australian Research Council.