Journal article

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

Peng Lei, Scott Ayton, David I Finkelstein, Loredana Spoerri, Giuseppe D Ciccotosto, David K Wright, Bruce XW Wong, Paul A Adlard, Robert A Cherny, Linh Q Lam, Blaine R Roberts, Irene Volitakis, Gary F Egan, Catriona A McLean, Roberto Cappai, James A Duce, Ashley I Bush

Nature Medicine | NATURE PUBLISHING GROUP | Published : 2012


Awarded by Alzheimers Research UK

Funding Acknowledgements

This work was supported by funds from the Australian Research Council, the National Health & Medical Research Council of Australia (NHMRC) and the Alzheimer's Association. The Victorian Brain Bank Network is supported by The University of Melbourne, The Mental Health Research Institute, The Alfred Hospital and the Victorian Forensic Institute of Medicine, and funded by Neurosciences Australia and the NHMRC. The authors thank Y-H. Hung, H. Kim, S.H. Bush and A. Sedjahtera for helpful discussion and technical assistance, H.N. Dawson (Duke University) for providing the tau-knockout mice, and TA. Rouault and D.L. Zhang (US National Institutes of Health) for MAP23 antibody.