Journal article
Mild worry symptoms predict decline in learning and memory in healthy older adults: A 2-year prospective cohort study
RH Pietrzak, P Maruff, M Woodward, J Fredrickson, A Fredrickson, JH Krystal, SM Southwick, D Darby
American Journal of Geriatric Psychiatry | Published : 2012
Abstract
Objective: Theoretical models of cognitive aging are increasingly recognizing the importance of anxiety and depressive symptoms in predicting age-related cognitive changes and early dementia. This study examined the association between mild worry and depressive symptoms, and cognitive function in healthy, community-dwelling older adults. Method: A total of 263 healthy older adults participated in an observational prospective cohort study that assessed worry and depression symptoms, and a broad range of cognitive functions over a 2-year period. Results: Older adults with mildly elevated worry symptoms at baseline performed worse than older adults with minimal worry symptoms on measures of vis..
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Funding Acknowledgements
This work was supported by CogState, Ltd., Melbourne, Australia. Preparation of this report was supported in part by the Clinical Neurosciences Division of the National Center for Posttraumatic Stress Disorder, VA Connecticut Healthcare System, West Haven, Connecticut.Dr. Pietrzak receives partial salary support from CogState, Ltd., a cognitive test company that provided the cognitive tests used in this study. Dr. Maruff, Dr. Darby, Ms Fredrickson, and Ms. Fredrickson are full-time employees and Dr. Maruff and Dr. Darby are shareholders of CogState, Ltd.