SINGLE-01: A randomized, controlled trial comparing the efficacy and depth of insertion of single- and double-balloon enteroscopy by using a novel method to determine insertion depth

Abstract

Background: Single-balloon enteroscopy (SBE) was introduced as an alternative to double-balloon enteroscopy (DBE) for the investigation and management of small-bowel conditions. To date, there is only 1 randomized, controlled trial comparing SBE and DBE in a Western population. Objective: To compare the 2 instruments in a Western population to assess for differences in clinical outcomes and insertion depth (ID). A novel method to determine ID by counting folds on withdrawal was used. Design: Multicenter, randomized, controlled trial. Setting: University hospitals in Melbourne and Sydney, Australia. Patients: Patients with suspected or proven small-bowel disease. Interventions: SBE and DBE. M..