Journal article
The effects of malaria and intermittent preventive treatment during pregnancy on fetal anemia in Malawi
ET Rogawski, E Chaluluka, ME Molyneux, G Feng, SJ Rogerson, SR Meshnick
Clinical Infectious Diseases | OXFORD UNIV PRESS INC | Published : 2012
DOI: 10.1093/cid/cis597
Abstract
Background.Fetal anemia is common in malarious areas and is a risk factor for infant morbidity and mortality. Malaria during pregnancy may cause decreased cord hemoglobin (Hb) and fetal anemia among newborns. Intermittent preventive treatment during pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is protective against malaria but may also affect hematopoiesis and contribute to fetal anemia.Methods.Peripheral, placental, and cord blood were examined for malaria parasitemia and Hb concentration in a cross-section of 3848 mothers and infants delivered at Queen Elizabeth Central Hospital in Blantyre, Malawi between 1997 and 2006. Unconditional linear and logistic regressions were performed ..
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Awarded by Wellcome Trust
Funding Acknowledgements
[ "This work (data collection) was supported by a Wellcome Trust Career Development Fellowship (046012) and a Wellcome Senior Overseas Research Fellowship (063215) to S. J. R.", "S. J. R. has served as a consultant for GlaxoSmithKline as a member of the Asia Pacific Malaria Vaccine Advisory Group and has an Investigator Initiated Research Grant from Pfizer Inc. All other authors report no potential conflicts." ]