Journal article
Modeling extracellular electrical stimulation: II. Computational validation and numerical results
B Tahayori, H Meffin, S Dokos, AN Burkitt, DB Grayden
Journal of Neural Engineering | IOP Publishing Ltd | Published : 2012
Abstract
The validity of approximate equations describing the membrane potential under extracellular electrical stimulation (Meffin et al 2012 J. Neural Eng. 9 065005) is investigated through finite element analysis in this paper. To this end, the finite element method is used to simulate a cylindrical neurite under extracellular stimulation. Laplace's equations with appropriate boundary conditions are solved numerically in three dimensions and the results are compared to the approximate analytic solutions. Simulation results are in agreement with the approximate analytic expressions for longitudinal and transverse modes of stimulation. The range of validity of the equations describing the membrane p..
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Awarded by Victorian Life Sciences Computation Initiative (VLSCI) on its Peak Computing Facility at the University of Melbourne, an initiative of the Victorian Government
Funding Acknowledgements
This research was supported by the Australian Research Council (ARC) through its Special Research Initiative (SRI) in Bionic Vision Science and Technology grant to Bionic Vision Australia (BVA). The Bionics Institute acknowledges the support it receives from the Victorian Government through its Operational Infrastructure Support Program. This research was supported by a Victorian Life Sciences Computation Initiative (VLSCI) grant number VR0138 on its Peak Computing Facility at the University of Melbourne, an initiative of the Victorian Government.