Binaural speech processing in individuals with auditory neuropathy

G Rance; MM Ryan; P Carew; LA Corben; E Yiu; J Tan; MB Delatycki

Journal article

Binaural speech processing in individuals with auditory neuropathy

G Rance, MM Ryan, P Carew, LA Corben, E Yiu, J Tan, MB Delatycki

Neuroscience | Published : 2012

DOI: 10.1016/j.neuroscience.2012.08.054

Abstract

Auditory neuropathy disrupts the neural representation of sound and may therefore impair processes contingent upon inter-aural integration. The aims of this study were to investigate binaural auditory processing in individuals with axonal (Friedreich ataxia) and demyelinating (Charcot-Marie-Tooth disease type 1A) auditory neuropathy and to evaluate the relationship between the degree of auditory deficit and overall clinical severity in patients with neuropathic disorders.Twenty-three subjects with genetically confirmed Friedreich ataxia and 12 subjects with Charcot-Marie-Tooth disease type 1A underwent psychophysical evaluation of basic auditory processing (intensity discrimination/temporal ..

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University of Melbourne Researchers

Gary Rance Author

Peter Carew Author

Eppie Yiu Author

Martin Delatycki Author

Grants

Funding Acknowledgements

This work was supported by the Friedreich Ataxia Research Alliance (FARA USA) and the Friedreich Ataxia Research Association (FARA Australasia). G.R. holds the Wagstaff Research Fellowship in Otolaryngology. M.B.D. is a NHMRC Practitioner Fellow.