Journal article

Ccl2/Cx3cr1 Knockout Mice Have Inner Retinal Dysfunction but Are Not an Accelerated Model of AMD

Kirstan A Vessey, Ursula Greferath, Andrew I Jobling, Joanna A Phipps, Tracy Ho, Michelle Waugh, Erica L Fletcher

Investigative Ophthalmology and Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2012

DOI: 10.1167/iovs.12-10650

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Grants

Awarded by NHMRC

Funding Acknowledgements

Supported by the NHMRC project Grants 566814 and 1021918 (ELF); by the American Health Assistance Foundation; Macular Degeneration Research grant (ELF); and a Victoria's Science Agenda grant (ELF).

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Keywords

Ophthalmology
Chemokine Ccl2
Electroretinography
Cx3c Chemokine Receptor 1
Microglia
Receptors, Chemokine
Mouse
Complement Factor-H
Life Sciences & Biomedicine
Retina
Microscopy, Electron
Science & Technology
Mice, Inbred C57bl
Genotype
Animal-Model
Immunohistochemistry
Mice, Knockout
Activated Microglia
Animals
Mutation
Mice
Disease Models, Animal
Bruch Membrane
Rat Retina
Rod
Retinopathy
Macular Degeneration
Microglial Cells
Accumulation