IS ALDOSTERONE SECRETION UNDER DOPAMINERGIC CONTROL

Abstract

The case for a role for dopamine in aldosterone control is far from proven and rests largely on the aldosterone response to metoclopramide administration. The mechanism by which metoclopramide stimulates aldosterone secretion remains to be defined, and further work is necessary to determine whether or not this metoclopramide effect is via blockade of a maximum tonic dopaminergic inhibition of aldosterone production.