Hypometabolism precedes limbic atrophy and spontaneous recurrent seizures in a rat model of TLE

Bianca Jupp; John Williams; David Binns; Rodney J Hicks; Lisa Cardamone; Nigel Jones; Sandra Rees; Terence J O'Brien

Journal article

Hypometabolism precedes limbic atrophy and spontaneous recurrent seizures in a rat model of TLE

Bianca Jupp, John Williams, David Binns, Rodney J Hicks, Lisa Cardamone, Nigel Jones, Sandra Rees, Terence J O'Brien

EPILEPSIA | WILEY | Published : 2012

DOI: 10.1111/j.1528-1167.2012.03525.x

University of Melbourne Researchers

Nigel Jones Author Medicine - Royal Melbourne Hospital

Sandra Rees Author Anatomy and Physiology

Terry O'Brien Author Medicine - Royal Melbourne Hospital

Rodney Hicks Author Medicine - St Vincent's Hospital

Related Projects (1)

The Effect of Stress and Hypercortisolaemia on Limbic Epileptogenesis & Affective Disorder.

This project has the potential to provide novel insights about the causal connections between stress, psychiatric illness (specifically anxi..

Grants

Awarded by NHMRC

Funding Acknowledgements

The authors wish to thank Milosh Vosmanski, from Austin Health, Heidelberg, Victoria, Australia for the electrodes used in this study and Marnie Collins from the Department of Mathematics and Statistics, The University of Melbourne, for advice regarding the statistical analysis. The study was supported by the Australian Government funded CRC for Biomedical Development and a NHMRC Project Grant to TJ O'Brien and S Rees (#400088).