A systematic review of stereotactic radiotherapy ablation for primary renal cell carcinoma

Abstract

OBJECTIVE • To critically assess the use of stereotactic ablative body radiotherapy (SABR) for the treatment of primary renal cell carcinoma with particular focus on local control and toxicity outcomes. METHODS • A systematic search on PubMed was performed in January 2012 independently by two radiation oncologists using structured search terms. • Secondary manual searches were performed on citations in relevant publications and abstracts in major radiotherapy journals. • Outcomes, techniques, biological doses and scientific rigour of the studies were analysed. RESULTS • In total 10 publications (seven retrospective and three prospective) were identified. A wide range of techniques, doses and..