Journal article
Retinal venular calibre dilatation after intravitreal ranibizumab treatment for neovascular age-related macular degeneration
SS Wickremasinghe, RH Guymer, TY Wong, R Kawasaki, W Wong, S Qureshi
Clinical and Experimental Ophthalmology | WILEY | Published : 2012
Abstract
Background: To describe the changes in retinal vascular calibre in response to intravitreal ranibizumab injections in patients with neovascular age-related macular degeneration. Design: Prospective interventional case series. Participants: Treatment naïve patients with neovascular age-related macular degeneration were recruited over a 1-year period. Methods: Each patient received three monthly intravitreal injections according to a 'loading dose'. Retinal arteriolar and venular calibre was measured from digital fundus photographs and summarized as central retinal artery equivalent and central retinal vein equivalent at baseline and 3months. Main Outcome Measure: Central retinal artery equiva..
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Awarded by National Health and Medical Research Council (NHMRC)
Funding Acknowledgements
Drs Guymer and Wong are on advisory boards of Novartis and Pfizer and have received research funding, speaking fees, travel and accommodation from either/both companies. Drs Wickremasinghe's and Kawasaki's scholarships are supported by Novartis. This study was partially funded by a National Health and Medical Research Council (NHMRC) grant, 52993.