NLRP1 Inflammasome Activation Induces Pyroptosis of Hematopoietic Progenitor Cells
Seth L Masters, Motti Gerlic, Donald Metcalf, Simon Preston, Marc Pellegrini, Joanne A O'Donnell, Kate McArthur, Tracey M Baldwin, Stephane Chevrier, Cameron J Nowell, Louise H Cengia, Katya J Henley, Janelle E Collinge, Daniel L Kastner, Lionel Feigenbaum, Douglas J Hilton, Warren S Alexander, Benjamin T Kile, Ben A Croker
Immunity | CELL PRESS | Published : 2012
Awarded by Australian National Health and Medical Research Council (NHMRC)
Awarded by NATIONAL HUMAN GENOME RESEARCH INSTITUTE
Awarded by NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
We thank S. Mifsud, L. DiRago, and J. Corbin for excellent technical assistance and E. Lanera, S. Ross, S. Guzzardi, S. Brown, E. Salt, and M. Salzone for outstanding animal husbandry. We thank V. Dixit for Caspase-11-deficient mice. This work was supported by Project Grants (637367, 1002426), a Program Grant (461219), Fellowships (B.A.C., D.J.H., W.S.A., S.L.M., B.T.K.), and an Independent Research Institutes Infrastructure Support Scheme Grant (361646) from the Australian National Health and Medical Research Council (NHMRC); Fellowships from the Australian Research Council (B.A.C., B.T.K.), the Sylvia and Charles Viertel Foundation (B.T.K.), and the Cancer Council of Victoria (D.M.); the Australian Cancer Research Fund; the Australian Phenomics Network; and a Victorian State Government Operational Infrastructure Support Grant.