Journal article
Psychiatric history does not predict seizure outcome following temporal lobectomy for mesial temporal sclerosis
SJ Adams, D Velakoulis, AH Kaye, NM Corcoran, TJ O'Brien
Epilepsia | Published : 2012
Abstract
Purpose: A lifetime psychiatric history has been reported to be associated with poorer seizure outcome following temporal lobectomy for drug-resistant focal epilepsy, but it remains unclear whether this is confounded by the nature of the epileptogenic pathology. Here we examined this association in a pathologically homogeneous group of patients with mesial temporal sclerosis (MTS). Methods: The study population included 72 consecutive patients who underwent a temporal lobectomy for drug resistant temporal lobe epilepsy (TLE) and had histopathologically proven MTS. All patients were assessed preoperatively by a neuropsychiatrist. Chi-square analysis was undertaken to look for demographic, cli..
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Funding Acknowledgements
Dr. Adams has received an Epilepsy Fellowship awarded by an Epilepsy Society of Australia-UCB Epilepsy Fellowship. Dr. Velakoulis receives royalties from ACER for publication of the NUCOG and has received funding from the National Health and Medical Research Council (Australia). Professor Andrew Kaye reports no disclosures. Dr. Corcoran is married to Dr. Adams and otherwise reports no disclosures. Dr. O'Brien has received research grant support and speakers fees from UCB Pharm, Janssen-Cilag, and Sanofi-Adventis. He has received research grant support from the NHMRC. We confirm that we have read the Journal's position on issues involved in ethical publication and affirm that this report is consistent with those guidelines.