Analysis of LRRK2 accessory repeat domains: prediction of repeat length, number and sites of Parkinson's disease mutations

Ryan D Mills; Terrence D Mulhern; Heung-Chin Cheng; Janetta G Culvenor

Journal article

Analysis of LRRK2 accessory repeat domains: prediction of repeat length, number and sites of Parkinson's disease mutations

Ryan D Mills, Terrence D Mulhern, Heung-Chin Cheng, Janetta G Culvenor

Biochemical Society Transactions | PORTLAND PRESS LTD | Published : 2012

DOI: 10.1042/BST20120088

University of Melbourne Researchers

Terry Mulhern Author Biochemistry and Pharmacology

Heung-Chin Cheng Author Biochemistry and Pharmacology

Janetta Culvenor Author Clinical Pathology

Related Projects (1)

How active LRRK2 causes Parkinson's disease

Parkinson's disease afflicts 100,000 Australians. Mutations in the recently identified enzyme Leucine-rich Repeat Kinase-2 are a common caus..

Grants

Awarded by Australian National Health and Medical Research Council

Funding Acknowledgements

We thank the Australian National Health and Medical Research Council [project grant number 566743] and the Australian Brain Foundation for financial support. R. D. M. was supported by an Australian Postgraduate Research Award, a Dowd Neuroscience Fellowship and an Australian Institute of Nuclear Science and Engineering Award.