Journal article
A model to measure fluid outflow in rabbit capsules post glaucoma implant surgery
DQ Nguyen, CM Ross, YQ Li, S Pandav, B Gardiner, D Smith, AC How, JG Crowston, MA Coote
Investigative Ophthalmology and Visual Science | Published : 2012
Abstract
PURPOSE. Prior models of glaucoma filtration surgery assess bleb morphology, which does not always reflect function. Our aim is to establish a model that directly measures tissue hydraulic conductivity of postsurgical outflow in rabbit bleb capsules following experimental glaucoma filtration surgery. METHODS. Nine rabbits underwent insertion of a single-plate pediatric Molteno implant into the anterior chamber of their left eye. Right eyes were used as controls. The rabbits were then allocated to one of two groups. Group one had outflow measurements performed at 1 week after surgery (n=5), and group two had measurements performed at 4 weeks (n = 4). Measurements were performed by cannulating..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
Supported in part by Operational Infrastructure funding from the Victorian Government (to The Centre for Eye Research Australia), Dorothy Adele Edols Charitable Trust, Irene Lo and Department of Pathology, St. Vincent's Hospital Melbourne, Melbourne, Australia, and National Health and Medical Research Council Grant 529918.