Journal article

Effect of Wolbachia on insecticide susceptibility in lines of Aedes aegypti

NM Endersby, AA Hoffmann

Bulletin of Entomological Research | CAMBRIDGE UNIV PRESS | Published : 2013


Two stable infections of Wolbachia pipientis, wMelPop and wMel, now established in Aedes aegypti, are being used in a biocontrol program to suppress the transmission of dengue. Any effects of Wolbachia infection on insecticide resistance of mosquitoes may undermine the success of this program. Bioassays of Ae. aegypti were conducted to test for differences in response to insecticides between Wolbachia infected (wMelPop, wMel) and uninfected lines. Insecticides screened were bifenthrin, the pyrethroid commonly used for adult knockdown, as well as larvicides: Bacillus thuringiensis var. israelensis, the organophosphate, temephos and the insect growth regulator, s-methoprene. While differences ..

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Funding Acknowledgements

We appreciate the technical assistance given by Vanessa White, Kelly Richardson, Jason Axford, Ashley Callahan, Alen Rako and Yeap Heng Lin. Thanks to Scott Ritchie, David Walker, Tim Hurst and Peter Ryan for insecticide samples and advice. The study was funded in part by a grant from the Foundation for the National Institutes of Health through the Vector-Based Transmission of Control: Discovery Research (VCTR) program of the Grand Challenges in Global Health Initiative of the Bill & Melinda Gates Foundation and also by the CSIRO Cluster Collaboration Fund 'Urbanism, Climate Change and Health' and the National Health and Medical Research Council.