Hsp72 preserves muscle function and slows progression of severe muscular dystrophy
Stefan M Gehrig, Chris van der Poel, Timothy A Sayer, Jonathan D Schertzer, Darren C Henstridge, Jarrod E Church, Severine Lamon, Aaron P Russell, Kay E Davies, Mark A Febbraio, Gordon S Lynch
NATURE | NATURE PUBLISHING GROUP | Published : 2012
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Awarded by National Health and Medical Research Council (NHMRC)
Awarded by Medical Research Council
We thank R. Koopman, J. G. Ryall and G. I. Lancaster for comments; J. Trieu, B. G. Gleeson, T. Naim and A. Chee for technical support; and C. Angelini and the Neuromuscular bank of tissues and DNA samples - Telethon Network of Genetic Biobanks for the provision of human muscle specimens. We thank N-Gene R&D Inc. USA for providing the BGP-15 compound. This study was supported in part by research grants from the National Health and Medical Research Council (NHMRC; project numbers 1009114 to G. S. L. and 472650 and 1004441 to M.A.F.), Association Francaise contre les Myopathies (France, to G. S. L.) and the Muscular Dystrophy Association (USA, to G. S. L.). M. A. F. is a Senior Principal Research Fellow of the NHMRC. A. P. R. was supported by a NHMRC Biomedical career Development Award. S. L. was supported by a postdoctoral fellowship from the Swiss National Science Foundation. S. M. G. was supported by a National Heart Foundation Postgraduate Scholarship (Australia). D. C. H. was supported by a National Heart Foundation Post-Doctoral Fellowship.