Journal article

Rubella control in Papua New Guinea: Age-specific immunity informs strategies for introduction of rubella vaccine

M Riddell, N Senn, CJ Clements, L Hobday, B Cowie, J Kurubi, A Kevin, P Siba, JC Reeder, C Morgan

Vaccine | ELSEVIER SCI LTD | Published : 2012

Abstract

Aim: To determine the age specific immunity profile for rubella from three discrete study populations in Papua New Guinea, and to inform policy regarding the possible introduction of rubella vaccine. Background: In 2005, the Western Pacific Region (WPR), of which Papua New Guinea (PNG) is a member state, declared the goal of regional measles elimination by 2012. Recently, WPR has incorporated an accelerated control goal for rubella and congenital rubella syndrome (CRS). PNG currently recommends two doses of measles vaccination at 6 and 9 months of age with a monovalent measles vaccine, which does not include rubella vaccine. Methods: Convenience samples were collected from 1326 eligible part..

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University of Melbourne Researchers

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Funding Acknowledgements

The authors thank Matthew Omena, Sauli Bebes and Doris Manong and staff at the PNG Institute for Medical Research in Goroka and Yagaum as well as staff at the Central Public Health Laboratory, Port Moresby for assistance in specimen collection and testing. We appreciate staff at the World Health Organization, Port Moresby for their assistance in country and with specimen transport. We thank all participants who agreed to provide specimens for this study. The catalytic modelling techniques used in this study were based on those used in the infectious disease modelling course developed by Emilia Vynnycky, Richard White and Azra Ghani of the London School of Hygiene and Tropical Medicine, London, United Kingdom. No specific funding was obtained to support this study. However the authors acknowledge funding for the individual studies which enabled this work. Burnet authors acknowledge the contribution to this work of the Victorian Operational Infrastructure Support Program. The EPO study was supported by UNICEF. The Well Baby Study was supported by the RE Ross Trust, Victoria through the PNG Child Health Research Fellowship. The Madang Fever Aetiology study was funded by the PNG Institute for Medical Research and The Australian National Health and Medical Research Council.