Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim

Diane Moujalled; Ross Weston; Holly Anderton; Robert Ninnis; Pranay Goel; Andrew Coley; David CS Huang; Li Wu; Andreas Strasser; Hamsa Puthalakath

Journal article

Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim

Diane Moujalled, Ross Weston, Holly Anderton, Robert Ninnis, Pranay Goel, Andrew Coley, David CS Huang, Li Wu, Andreas Strasser, Hamsa Puthalakath

EMBO Rep. | WILEY | Published : 2011

DOI: 10.1038/embor.2010.190

University of Melbourne Researchers

Diane Moujalled Author Medical Biology (W.E.H.I.)

David Huang Author Medical Biology (W.E.H.I.)

Andreas Strasser Author Medical Biology (W.E.H.I.)

Grants

Awarded by National Health and Medical Research Council

Awarded by Leukemia and Lymphoma Society

Funding Acknowledgements

We thank L. O'Connor, N. Hoogenraad and D. L. Vaux for helpful discussion; L. A. O'Reilly, P. Bouillet, D. Chau, J. Silke and P. Ekert for reagents and cell lines and I. Wertz for the beta TrCP1 construct. H. P. is supported by Australian Research Council Future Fellowship and National Health and Medical Research Council project grant (487311). A. S. is supported by the Leukemia and Lymphoma Society (7413) and the National Health and Medical Research Council (461221, 461299). D. M. is supported by a La Trobe Postgraduate Award and Cooperative Research Centre for Biomarker Translation.