Journal article

Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak

Rachel T Uren, Grant Dewson, Lin Chen, Stephanie C Coyne, David CS Huang, Jerry M Adams, Ruth M Kluck

The Journal of Cell Biology | ROCKEFELLER UNIV PRESS | Published : 2007

DOI: 10.1083/jcb.200606065

University of Melbourne Researchers

Rachel Uren Author Anatomy and Physiology

Jerry Adams Author Medical Biology (W.E.H.I.)

David Huang Author Medical Biology (W.E.H.I.)

Grant Dewson Author Medical Biology (W.E.H.I.)

Ruth Kluck Author Medical Biology (W.E.H.I.)

Grants

Awarded by NATIONAL CANCER INSTITUTE

Awarded by NCI NIH HHS

Citation metrics

95Web of Science

Keywords

Bh3 Interacting Domain Death Agonist Protein

Neoplasm Proteins

Myeloid Cell Leukemia Sequence 1 Protein

Mitochondrial Membranes

Pro-Apoptotic Proteins

Science & Technology

Bcl-2 Homologous Antagonist-Killer Protein

Peptide Fragments

Proto-Oncogene Proteins C-Bcl-2

Proto-Oncogene Proteins

Cytochrome-C Release

Life Sciences & Biomedicine

Bh3-Only Proteins