Journal article
The prognosis of idiopathic generalized epilepsy
U Seneviratne, M Cook, W D'Souza
Epilepsia | Published : 2012
Abstract
Prognosis describes the trajectory and long-term outcome of a condition. Most studies indicate a better prognosis in idiopathic generalized epilepsy (IGE) in comparison with other epilepsy syndromes. Studies looking at the long-term outcome of different IGE syndromes are relatively scant. Childhood absence epilepsy appears to have a higher rate of remission compared to juvenile absence epilepsy. In absence epilepsies, development of myoclonus and generalized tonic-clonic seizures predicts lower likelihood of remission. Although most patients with juvenile myoclonic epilepsy (JME) achieve remission on antiepileptic drug therapy, <20% appear to remain in remission without treatment. Data on th..
View full abstractGrants
Funding Acknowledgements
Dr Seneviratne reports no disclosures. Professor Cook has received speaker honoraria from UCB Pharma and Sanofi Australia and travel honoraria from UCB Pharma and SciGen. He has received research grants from National Health and Medical Research Council (Australia), and Australian Research Council. He has also received a Science, Technology, and Innovation Grant from the State Government of Victoria, Australia. A/Professor D'Souza has received travel, investigator-initiated, and speaker honoraria from UCB Pharma, educational grants from Novartis Pharmaceuticals and Pfizer Pharmaceuticals, educational, travel and fellowship grants from GSK Neurology Australia, and honoraria from SciGen Pharmaceuticals. We confirm that we have read the Journal's position on issues involved in ethical publication and affirm that this report is consistent with those guidelines.