The dorsal motor nucleus of the vagus and regulation of pancreatic secretory function

Abstract

New Findings: • What is the Topic of this review? This review describes new evidence for the control of pancreatic exocrine and endocrine secretion by the dorsal motor nucleus of the vagus. It describes the effects of several gastrointestinal peptides on pancreatic secretion and considers their sites of action in the vago-vagal reflex pathway. • What advances does it highlight? This review draws together recent electrophysiological, anatomical and pharmacological studies to provide a state-of-art view of the parasympathetic control of the exocrine and endocrine pancreas. Recent investigation of the factors and pathways that are involved in regulation of pancreatic secretory function (PSF) ha..