Family studies of individuals with eyelid myoclonia with absences
Lynette G Sadleir, Danya Vears, Brigid Regan, Natalie Redshaw, Andrew Bleasel, Ingrid E Scheffer
EPILEPSIA | WILEY | Published : 2012
PURPOSE: Eyelid myoclonia with absences (EM) is an uncommon type of absence seizure associated with a variety of epilepsy syndromes. The syndrome of epilepsy with EM (EMA) has been proposed to denote the onset of frequent EM induced by eye closure and photic stimulation beginning in childhood. The clinical genetics of EMA has not been well characterized, although a family history of seizures is not infrequent. METHODS: Individuals with EMA were ascertained by referral and through the investigators' clinical practices. All available family members were assessed for seizures using a validated seizure questionnaire. Electroclinical data were obtained on each proband and all affected family memb..View full abstract
Health Research Council of New Zealand, Cure Kids New Zealand, National Health and Medical Research Council of Australia.