Inhibitory Control During Smooth Pursuit in Parkinson's Disease and Huntington's Disease
Tracy Henderson, Nellie Georgiou-Karistianis, Owen White, Lynette Millist, David R Williams, Andrew Churchyard, Joanne Fielding
MOVEMENT DISORDERS | WILEY-BLACKWELL | Published : 2011
The basal ganglia are involved in the preferential selection and suppression of competing responses. Parkinson's disease and Huntington's disease are 2 prototypical basal ganglia disorders that feature impaired inhibitory control, a function of poor conflict resolution. Previous saccadic studies showed that individuals with Parkinson's disease experience difficulty suppressing unwanted ocular motor responses, whereas evidence for a similar difficulty in Huntington's disease is more equivocal. Relative to saccades, few research studies have examined inhibitory control processes in the context of an ongoing smooth pursuit task. In this study, we examined the ability of 16 patients with Parkins..View full abstract
This research project was fully funded by Monash University as part of a Doctor of Psychology (Clinical Neuropsychology) postgraduate degree.