Management of local recurrences in the irradiated bladder: a systematic review.

Abstract

• To review and report the management and outcomes of patients with recurrence of bladder cancer (BC) who initially had complete response to bladder conservation therapy. • A comprehensive review of all published literature reporting outcomes in bladder-sparing treatments for muscle-invasive BC (MIBC) was conducted in a systematic fashion by two independent authors across several databases including PubMed and Medline using the following keywords, alone or in combination: bladder cancer, radiotherapy, recurrence, outcome, cystoscopy, follow up, combined modality therapy, and organ preservation. • In all, 17 studies reporting prevalence and management of local recurrences were included in fin..