Journal article

Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation

CL Scott, M Schuler, VS Marsden, A Egle, M Pellegrini, D Nesic, S Gerondakis, SL Nutt, DR Green, A Strasser

J. Cell Biol. | ROCKEFELLER UNIV PRESS | Published : 2004

DOI: 10.1083/jcb.200310041

Grants

Awarded by NCI NIH HHS

Awarded by NIAID NIH HHS

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Keywords

Pathways
Mice
Cell-Death
Drug Resistance, Neoplasm
Lines
Caspases
Animals
Cell Line, Tumor
Incidence
Caspase
C-Myc
Fetus
Proto-Oncogene Proteins C-Myc
Hepatocytes
Bcl-2
Apoptotic Protease-Activating Factor 1
Life Sciences & Biomedicine
Fibroblasts
Radiation Chimera
Resistance
Activation
Tumor Suppressor Proteins
Mitochondria
Transgenes
Apoptosis
Lymphoma
Science & Technology
Caspase 9
Deficiency
Cell Transformation, Neoplastic
Proteins
Cell Biology
Apaf-1
Disease Progression
Mice, Knockout
Cells, Cultured
Transgenic Mice
Cancer