A Systematic Review of the Use of Growth Factors in Human Periodontal Regeneration

Abstract

BACKGROUND: There is a large body of evidence using cells and animal models demonstrating the effectiveness of growth factors in periodontal regeneration. However, there appears to be minimal literature comparing the efficacy of growth factors in human periodontal regeneration compared to other techniques and procedures. Therefore, the aim of this study is to perform a systematic review of human studies using growth factors for periodontal regeneration and to compare the efficacy of these growth factors to other accepted techniques for periodontal regeneration. METHODS: An electronic and manual search based on agreed search phrases between the primary investigator and a secondary investigato..