The BH3-Only Proteins Bim and Puma Cooperate to Impose Deletional Tolerance of Organ-Specific Antigens
Daniel HD Gray, Fiona Kupresanin, Stuart P Berzins, Marco J Herold, Lorraine A O'Reilly, Philippe Bouillet, Andreas Strasser
Immunity | CELL PRESS | Published : 2012
Awarded by Australian National Health and Medical Research Council (NHMRC)
Awarded by Leukemia and Lymphoma Society (New York; Specialized Center of Research)
Awarded by National Cancer Institute (National Institutes of Health)
We gratefully acknowledge C. Thompson (Memorial Sloan-Kettering Cancer Center, New York) for the kind gift of Bak<SUP>-/-</SUP> mice, N. Danial (Dana-Farber Cancer Institute, Boston) for Bad<SUP>-/-</SUP> mice, and T. Jacks (Massachusetts Institute of Technology, Cambridge, MA, USA) for Trp53<SUP>-/-</SUP> mice; K. Mason and D. Huang for the provision of Bax<SUP>-/-</SUP>Bak<SUP>-/-</SUP> mouse fetal livers; G. Dewson for the provision of antibodies; G. Siciliano, K. Vella, K. Trueman, and G.-F. Dabrowski for animal care; and B. Holbert, C. Young, A. Policheni, and the WEHI Cytometry and Histology Facilities for technical assistance. This work was supported by the Australian National Health and Medical Research Council (NHMRC project grants 637332 and 1009145, Australia Fellowship to A.S., and Career Development Fellowship (637353) to D.H.D.G), the Juvenile Diabetes Foundation, the Leukemia and Lymphoma Society (New York; Specialized Center of Research grant 7413), and the National Cancer Institute (National Institutes of Health; CA 43540). This work was made possible through Victorian State Government Operational Infrastructure Support and the Australian Government NHMRC Independent Research Institute Infrastructure Support Scheme.