Incidence and seroprevalence of dengue virus infections in Australian travellers to Asia

I Ratnam; J Black; K Leder; BA Biggs; E Matchett; A Padiglione; I Woolley; T Panagiotidis; T Gherardin; L Pollissard; C Demont; C Luxemburger; J Torresi

Journal article

Incidence and seroprevalence of dengue virus infections in Australian travellers to Asia

I Ratnam, J Black, K Leder, BA Biggs, E Matchett, A Padiglione, I Woolley, T Panagiotidis, T Gherardin, L Pollissard, C Demont, C Luxemburger, J Torresi

European Journal of Clinical Microbiology and Infectious Diseases | Published : 2012

DOI: 10.1007/s10096-011-1429-1

Abstract

The purpose of this study was to estimate the incidence density and prevalence of dengue virus infection in Australian travellers to Asia. We conducted a multi-centre prospective cohort study of Australian travellers over a 32-month period. We recruited 467 travellers (≥16 years of age) from three travel clinics who intended to travel Asia, and 387 (82.9%) of those travellers completed questionnaires and provide samples pre- and post-travel for serological testing for dengue virus infection. Demographic data, destination countries and history of vaccinations and flavivirus infections were obtained. Serological testing for dengue IgG and IgM by enzyme-linked immunosorbent assay (ELISA) (PanBi..

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University of Melbourne Researchers

Jim Black Author

Beverley-Ann Biggs Author

Joseph Torresi Author

Grants

Funding Acknowledgements

This study was funded by an investigator-initiated unrestricted grant from Sanofi-Pasteur. The authors Laurence Pollissard, Clarisse Demont and Christine Luxemburger are employees of Sanofi-Pasteur. Joseph Torresi has received a speaking honoraria from Sanofi-Pasteur.