Journal article
ironXS: High-school screening for hereditary haemochromatosis is acceptable and feasible
MB Delatycki, M Wolthuizen, V Collins, E Varley, J Craven, KJ Allen, LC Gurrin, M Aitken, MK Trembath, L Bond, GR Wilson, SEM Stephenson, I Macciocca, C Hickerton, PJ Lockhart, SA Metcalfe
European Journal of Human Genetics | NATURE PUBLISHING GROUP | Published : 2012
Abstract
As the results of the Human Genome Project are realised, screening for genetic mutations that predispose to preventable disease is becoming increasingly possible. How and where such screening should best be offered are critical, unanswered questions. This study aimed to assess the acceptability and feasibility of genetic screening for preventable disease, using the model of hereditary haemochromatosis, in high-school students. Screening was offered for the HFE C282Y substitution to 17 638 students. Questionnaires were administered at the time of screening (Q1) and approximately 1 month after results were communicated (Q2). Outcomes assessed were uptake of screening, change in scores of valid..
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Awarded by Jack Brockhoff Foundation
Funding Acknowledgements
This study was funded by the National Health and Medical Research Council (491224) and the Jack Brockhoff Foundation. MBD is a National Health and Medical Research Council (Australia) Practitioner Fellow. KJA is Viertel Senior Medical Research Fellow.