Journal article

9q31.2-rs865686 as a Susceptibility Locus for Estrogen Receptor-Positive Breast Cancer: Evidence from the Breast Cancer Association Consortium

Helen Warren, Frank Dudbridge, Olivia Fletcher, Nick Orr, Nichola Johnson, John L Hopper, Carmel Apicella, Melissa C Southey, Maryam Mahmoodi, Marjanka K Schmidt, Annegien Broeks, Sten Cornelissen, Linda M Braaf, Kenneth R Muir, Artitaya Lophatananon, Arkom Chaiwerawattana, Surapon Wiangnon, Peter A Fasching, Matthias W Beckmann, Arif B Ekici Show all

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION | AMER ASSOC CANCER RESEARCH | Published : 2012

Grants

Awarded by United States (US) National Cancer Institute, NIH


Awarded by University of Melbourne


Awarded by ABCS: Dutch Cancer Society


Awarded by Cancer Research UK


Awarded by UK Medical Research Council


Awarded by BCAC: Cancer Research UK


Awarded by European Community's Seventh Framework Programme


Awarded by European Union COST program


Awarded by CECILE: Fondation de France


Awarded by Institut National du Cancer (INCa)


Awarded by Association pour la Recherche contre le Cancer (ARC)


Awarded by Agence Francaise de Securite Sanitaire de l'Environnement et du Travail (AFSSET - ANSES)


Awarded by Agence Nationale de la Recherche (ANR)


Awarded by Fondo de Investigacion Sanitario


Awarded by NIH


Awarded by Lon V Smith Foundation


Awarded by California Breast Cancer Research Fund


Awarded by GESBC: Deutsche Krebshilfe e.V.


Awarded by Baden-Wurttemberg through the Medical Faculty of the University of Ulm


Awarded by GC-HBOC: Deutsche Krebshilfe


Awarded by GENICA: Federal Ministry of Education and Research (BMBF) Germany


Awarded by HEBCS: Helsinki University Central Hospital Research Fund, Academy of Finland


Awarded by HUBCS: German Federal Ministry for Research and Education


Awarded by Academy of Finland


Awarded by Government Funding (EVO) of Kuopio University Hospital


Awarded by NHMRC


Awarded by US Army Medical Research and Materiel Command


Awarded by LMBC: 'Stichting tegen Kanker'


Awarded by MARIE: Deutsche Krebshilfe e.V.


Awarded by Federal Ministry of Education and Research (BMBF) Germany


Awarded by Associazione Italiana per la Ricerca sul Cancro


Awarded by MCBCS: NIH


Awarded by Specialized Program of Research Excellence (SPORE) in Breast Cancer


Awarded by MCCS: Australian National Health and Medical Research Council


Awarded by NC-BCFR: US National Cancer Institute, NIH


Awarded by Cancer Care Ontario


Awarded by Cancer Prevention Institute of California


Awarded by OFBCR: US National Cancer Institute, NIH


Awarded by Northern California Cancer Center


Awarded by ORIGO: Dutch Cancer Society


Awarded by Biobanking and Biomolecular Resources Research Infrastructure


Awarded by RBCS: Dutch Cancer Society


Awarded by SASBAC: NIH


Awarded by SEARCH: Programme grant from Cancer Research UK


Awarded by UCIBCS: US NIH


Awarded by Medical Research Council


Awarded by National Institute for Health Research


Awarded by The Francis Crick Institute


Awarded by NATIONAL CANCER INSTITUTE


Funding Acknowledgements

This work was supported by the following sources - ABCFS: National Health and Medical Research Council of Australia, the New South Wales Cancer Council; the Victorian Health Promotion Foundation (Australia); the United States (US) National Cancer Institute, NIH [RFA CA 06 503]; and through cooperative agreements with members of the Breast Cancer Family Registry (CFR) and principal investigators. The University of Melbourne [U01 CA69638] contributed data to this study. ABCS: Dutch Cancer Society [NKI 2001-2423, 2007-3839] and Dutch National Genomics Initiative. ACP: Breast Cancer Research Trust, UK. BBCC: ELAN program of the University Hospital of Erlangen. BBCS: Cancer Research UK [C150/A5660 and C1178/A3947]; Break through Breast Cancer; and NHS funding to the NIHR Biomedical Research Centre and the National Cancer Research Network (NCRN). H. Warren is funded by the UK Medical Research Council [G0801414]. BCAC: Cancer Research UK [C1287/A10118, C1287/A12014] and the European Community's Seventh Framework Programme under grant agreement no. 223175 (HEALTH-F2-2009-223175) (COGS). BCAC meetings have been funded by the European Union COST program [BM0606]. BIGGS: NIHR Comprehensive Biomedical Research Centre, Guy's & St. Thomas' NHS Foundation Trust in partnership with King's College London [to E.J. Sawyer]; Oxford Biomedical Research Centre (to I. Tomlinson]. BSUCH: Helmholtz Society; German Cancer Research Center; and Dietmar-Hopp Foundation. CECILE: Fondation de France [2004012618, 2007005156]; Institut National du Cancer (INCa) [2007-1/SPC2, 2008-1-CP-4, 2009-1-SHS/SP-04]; Association pour la Recherche contre le Cancer (ARC) [2008-1-CP-4]; Agence Francaise de Securite Sanitaire de l'Environnement et du Travail (AFSSET - ANSES) [ST-2005-003, EST2008/1/26, and VS-2009-21]; Ligue contre le Cancer Grand Ouest; and Agence Nationale de la Recherche (ANR) [00047-05]. CGPS: Herlev Hospital; Chief Physician Johan Boserup; and Lise Boserup's Fund. CNIO-BCS: Genome Spain Foundation; the Red Tematica de Investigacion Cooperativa en Cancer and grants from the Asociacion Espanola Contra el Cancer; and the Fondo de Investigacion Sanitario [PI081583, PI081120]. CTS: California Breast Cancer Act of 1993; NIH [R01 CA77398]; the Lon V Smith Foundation [LVS39420]; and the California Breast Cancer Research Fund [contract 97-10500]. Collection of cancer incidence data used in this study was supported by the California Department of Public Health as part of the statewide cancer-reporting program mandated by California Health and Safety Code Section 103885. ESTHER: Baden-Wurttemberg Ministry of Science, Research and Arts. Additional cases were recruited in the context of the VERDI study that was supported by a grant from the Deutsche Krebshilfe (German Cancer Aid). GESBC: Deutsche Krebshilfe e.V. [70492]; and genotyping in part by the state of Baden-Wurttemberg through the Medical Faculty of the University of Ulm [P.685]. GC-HBOC: Deutsche Krebshilfe [107054]; the Dietmar-Hopp Foundation; the Helmholtz society; and the German Cancer Research Centre (DKFZ). GENICA: Federal Ministry of Education and Research (BMBF) Germany [01KW9975/5, 01KW9976/8, 01KW9977/0, 01KW0114]; Robert Bosch Foundation, Stuttgart; Deutsches Krebsforschungszentrum (DKFZ), Heidelberg; Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn; Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum, Germany. HABCS: Rudolf Bartling Foundation.HEBCS: Helsinki University Central Hospital Research Fund, Academy of Finland [132473]; Finnish Cancer Society; Nordic Cancer Union; and Sigrid Juselius Foundation. HMBCS: Hannelore Munke Stipend [to N. Bogdanova]. HUBCS: German Federal Ministry for Research and Education [RUS 08/017]. KARBAC: Swedish Cancer Society; Stockholm Cancer Society; and Gustav V Jubilee Foundation. KBCP: Finnish Cancer Society; Academy of Finland [127220], special Government Funding (EVO) of Kuopio University Hospital [5654113, 5501]; and strategic funding from the University of Eastern Finland. KConFab-AOCS: National Breast Cancer Foundation; National Health and Medical Research Council (NHMRC); Queensland Cancer Fund; Cancer Councils of New South Wales, Victoria, Tasmania and South Australia; and the Cancer Foundation of Western Australia. The kConFab Clinical Follow Up Study was funded by the NHMRC [145684, 288704, 454508]. Financial support for the AOCS was provided by the US Army Medical Research and Materiel Command [DAMD17-01-1-0729], the Cancer Council of Tasmania and Cancer Foundation of Western Australia and the NHMRC [199600]. G. Chenevix-Trench and P. Webb are supported by the NHMRC. LMBC: 'Stichting tegen Kanker' [232-2008, 196-2010]. MARIE: Deutsche Krebshilfe e.V. [70-2892-BR 1]; Hamburg Society; German Cancer Research Center; and the genotype work in part by the Federal Ministry of Education and Research (BMBF) Germany [01KH0402]. MBCSG: Ministero della Salute (Extraordinary National Cancer Program 2006 "Alleanza contro il Cancro", and "Progetto Tumori Femminili") (to P. Radice); Ministero dell'Universita e Ricerca (RBLAO3-BETH; to P. Radice); Fondazione Italiana per la Ricerca sul Cancro (Special Project "Hereditary tumors"); Associazione Italiana per la Ricerca sul Cancro (4017; to P. Peterlongo) and by funds from Italian citizens who allocated the 5/1000 share of their tax payment in support of the Fondazione IRCCS Istituto Nazionale Tumori, according to Italian laws (INT-Institutional strategic projects "5 x 1000"). MCBCS: NIH [CA122340]; Specialized Program of Research Excellence (SPORE) in Breast Cancer [CA116201]; the Komen Foundation for the Cure; and the Breast Cancer Research Foundation (BCRF). MCCS: Australian National Health and Medical Research Council [209057, 251533, 396414, 504711], with infrastructure support provided by the Cancer Council Victoria, and cohort recruitment partly funded by VicHealth. NC-BCFR: US National Cancer Institute, NIH [RFA-CA-06-503] and through cooperative agreements with members of the Breast Cancer Family Registry (BCFR) and Principal Investigators, including Cancer Care Ontario [U01 CA69467], the Cancer Prevention Institute of California [U01 CA69417], and The University of Melbourne [U01 CA69638]. Samples from the NC-BCFR were processed and distributed by the Coriell Institute for Medical Research. OBCS: Finnish Cancer Foundation; Academy of Finland; University of Oulu; and Oulu University Hospital. OFBCR: US National Cancer Institute, NIH [RFA-CA-06503] and through cooperative agreements with members of the Breast Cancer Family Registry (BCFR) and Principal Investigators, including Cancer Care Ontario [U01 CA69467], Northern California Cancer Center [U01 CA69417], and University of Melbourne [U01 CA69638] and by Cancer Care Ontario. ORIGO: Dutch Cancer Society [RUL 1997-1505]; and Biobanking and Biomolecular Resources Research Infrastructure [BBMRI-NL CP16]. RBCS: Dutch Cancer Society [DDHK 2004-3124, DDHK 2009-4318]. SASBAC: NIH [RO1 CA58427] [to P. Hillemanns and J.Liu]; and the Agency for Science, Technology and Research (A *STAR; Singapore). SBCS: Yorkshire Cancer Research; and Breast Cancer Campaign. SEARCH: Programme grant from Cancer Research UK [C490/A10124]. UCIBCS: US NIH [CA58860, CA92044] and the Lon V Smith Foundation [LVS39420]. UKBGS: Breakthrough Breast Cancer.