Language lateralization correlates with verbal memory performance in children with focal epilepsy
Regula Everts, A Simon Harvey, Leasha Lillywhite, Jacquie Wrennall, David F Abbott, Linda Gonzalez, Michael Kean, Graeme D Jackson, Vicki Anderson
EPILEPSIA | WILEY | Published : 2010
PURPOSE: Assessment of language dominance with functional magnetic resonance imaging (fMRI) and neuropsychological evaluation is often used prior to epilepsy surgery. This study explores whether language lateralization and cognitive performance are systematically related in young patients with focal epilepsy. METHODS: Language fMRI and neuropsychological data (language, visuospatial functions, and memory) of 40 patients (7-18 years of age) with unilateral, refractory focal epilepsy in temporal and/or frontal areas of the left (n = 23) or right hemisphere (n = 17) were analyzed. fMRI data of 18 healthy controls (7-18 years) served as a normative sample. A laterality index was computed to dete..View full abstract
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Awarded by Swiss Science Foundation
Awarded by National Health and Medical Research Council of Australia (NHMRC)
This study was enabled by a fellowship from the Swiss Science Foundation. (PBBE1-11924) and funding from the National Health and Medical Research Council of Australia (NHMRC Project Grant 226100, Project Grant 368650, Project Grant 318900, and Program Grant 400121.