Journal article

The role of abdominal adiposity and insulin resistance in dyslipidemia of chronic renal failure

P Lee, D ONeal, B Murphy, J Best

AMERICAN JOURNAL OF KIDNEY DISEASES | W B SAUNDERS CO-ELSEVIER INC | Published : 1997

Abstract

The atherogenic profile of high triglyceride, reduced high-density lipoprotein (HDL) cholesterol, and small low-density lipoprotein particle size found in patients on chronic hemodialysis is known to be associated with insulin resistance and abdominal obesity in the general population. To assess the influence of insulin resistance and abdominal adiposity on the lipid profile in subjects on hemodialysis, intravenous glucose tolerance test and dual-energy x-ray absorptiometry were performed in 26 nondiabetic subjects on hemodialysis and compared with 22 nondiabetic control subjects matched for age, sex, and body mass index. Subjects on hemodialysis were found to have higher triglyceride (133 m..

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