Liver X Receptors and Oxysterols Promote Ventral Midbrain Neurogenesis In Vivo and in Human Embryonic Stem Cells
Paola Sacchetti, Kyle M Sousa, Anita C Hall, Isabel Liste, Knut R Steffensen, Spyridon Theofilopoulos, Clare L Parish, Carin Hazenberg, Lars Ahrlund-Richter, Outti Hovatta, Jan-Ake Gustafsson, Ernest Arenas
Cell Stem Cell | CELL PRESS | Published : 2009
Awarded by Swedish Research Council
The authors are grateful to Drs. Magdalena Gbtz, Weimin Zhong, and Franqois Guillemot for their invaluable comments and critical support of this work. We also thank Heider Andre for comments and suggestions on the manuscript, Dr. Ruani Fernando for invaluable discussion and technical help on histology and imaging, and Johnny Soderlund for technical assistance. This work was supported by the Michael J. Fox Foundation, Swedish Foundation for Strategic Research (INGVAR and CEDB), European Union (Strokemap, NeuroStemCell), Karolinska Institutet, Petrus and Augusta Hedlunds Foundation, Swedish Research Council (VR2008:3287 and DBRM), and Norwegian Research Council to E.A., and grants from VIR to O.H., L.A.R., and J.-A.G. E.A. was supported by Swedish Royal Academy of Sciences and Knut and Alice Wallenberg Foundation, P.S. was supported by Norwegian Research Council, and A.C.H. was supported by Human Frontiers Science Program. C.L.P. was supported by an Australian National Health and Medical Research Council (NHMRC) CJ Martin Fellowship and NHMRC Career Development Award. J.-A.G. is shareholder and consultant of KaroBio AB and was supported by a grant from KaroBio AB.