An elevated apolipoprotein B/AI ratio is independently associated with microalbuminuria in male subjects with impaired fasting glucose
K-C Sung, E-J Rhee, H Kim, J-B Park, Y-K Kim, S Woo, AM Wilson
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES | ELSEVIER SCI LTD | Published : 2011
BACKGROUND AND AIMS: The ratio of apolipoprotein B/AI (apo B/AI) has been used as a marker to predict the risk of coronary artery disease. Recent studies have suggested an association between apolipoprotein B level and microalbuminuria in diabetic subjects. This study was performed to assess a possible association between the apo B/AI ratio and microalbuminuria in male subjects with impaired fasting glucose (IFG). METHODS AND RESULTS: In 1266 patients with fasting serum glucose level in the pre-diabetic range, urine albumin-to-creatinine ratio (UACR, μg mg(-1)) was measured from single morning voided urine. The presence of microalbuminuria was defined as a UACR between 30 and 299 μg mg(-1). ..View full abstract
Awarded by Samsung Biomedical Research Institute
This work was partially supported by the Samsung Biomedical Research Institute grant, SBRI C-A8-216-1.