Journal article

Identification of major ischemic change - Diffusion-weighted imaging versus computed tomography

PA Barber, DG Darby, PM Desmond, RP Gerraty, Q Yang, T Li, D Jolley, GA Donnan, BM Tress, SM Davis

Stroke | LIPPINCOTT WILLIAMS & WILKINS | Published : 1999


BACKGROUND AND PURPOSE: Thrombolytic therapy is not recommended in patients with CT changes of recent major infarction, which has been defined as reduced attenuation or cerebral edema involving >33% of the middle cerebral artery territory (European Cooperative Acute Stroke Study [ECASS] criteria). Diffusion-weighted imaging (DWI) is more sensitive than CT in detecting acute ischemia, and the combination of DWI, MR perfusion imaging, and MR angiography provides additional information from a single examination. We sought to determine whether DWI could identify the presence and extent of major ischemia as well as CT in hyperacute stroke patients. METHODS: Seventeen suspected hemispheric stroke ..

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