Journal article
Characteristics and short-term prognosis of perioperative myocardial infarction in patients undergoing noncardiac surgerya cohort study
PJ Devereaux, D Xavier, J Pogue, G Guyatt, A Sigamani, I Garutti, K Leslie, P Rao-Melacini, S Chrolavicius, H Yang, C MacDonald, A Avezum, L Lanthier, W Hu, S Yusuf
Annals of Internal Medicine | Published : 2011
Abstract
Background: Each year, millions of patients worldwide have a perioperative myocardial infarction (MI) after noncardiac surgery.Objective: To examine the characteristics and short-term outcome of perioperative MI.Design: Cohort study. (ClinicalTrials.gov registration number: NCT00182039)etting: 190 centers in 23 countries.Patients: 8351 patients included in the POISE (PeriOperative ISch-emic Evaluation) trial.Measurements: Four cardiac biomarker or enzyme assays were measured within 3 days of surgery. The definition of perioperative MI included either autopsy findings of acute MI or an elevated level of a cardiac biomarker or enzyme and at least 1 of the following defining features: ischemic ..
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Awarded by Instituto de Salud Carlos III (Ministerio de Sanidad y Consumo) in Spain
Funding Acknowledgements
Grant Support: By the Canadian Institutes of Health Research, the Commonwealth Government of Australia's National Health and Medical Research Council, the Instituto de Salud Carlos III (PI071071, Ministerio de Sanidad y Consumo) in Spain, the British Heart Foundation, and AstraZeneca.