Primary Tumor Hypoxia Recruits CD11b( )/Ly6C(med)/Ly6G( ) Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche

Jaclyn Sceneay; Melvyn T Chow; Anna Chen; Heloise M Halse; Christina SF Wong; Daniel M Andrews; Erica K Sloan; Belinda S Parker; David D Bowtell; Mark J Smyth; Andreas Moeller

Journal article

Primary Tumor Hypoxia Recruits CD11b( )/Ly6C(med)/Ly6G( ) Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche

Jaclyn Sceneay, Melvyn T Chow, Anna Chen, Heloise M Halse, Christina SF Wong, Daniel M Andrews, Erica K Sloan, Belinda S Parker, David D Bowtell, Mark J Smyth, Andreas Moeller

Cancer Research | AMER ASSOC CANCER RESEARCH | Published : 2012

DOI: 10.1158/0008-5472.CAN-11-3873

University of Melbourne Researchers

Belinda Parker Author The Sir Peter MacCallum Department of Oncology

Andreas Moller Author Medicine, Dentistry and Health Sciences

David Bowtell Author The Sir Peter MacCallum Department of Oncology

Grants

Funding Acknowledgements

The study was supported by Association of International Cancer Research project grant to A. Moller, State Trustees Australia Foundation scholarship to J. Sceneay, National Breast Cancer Foundation Fellowship to A. Moller and E.K. Sloan, National Health and Medical Research Council (NH&MRC) Australia Fellowship, NH&MRC Program Grant, and Victorian Cancer Agency support to M.J. Smyth, NH&MRC project grant to D.M. Andrews and E.K. Sloan, NHMRC CDA to B.S. Parker and D.M. Andrews, Cancer Research Institute Scholarship and Beaney Scholarship in Pathology to M.T. Chow, and NIH grant to E.K. Sloan.