The implications of heterogeneous DNA methylation for the accurate quantification of methylation

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Funding Acknowledgements

Alexander Dobrovic is the coinventor of intellectual property on MS-HRM and SMART-MSP held by the Peter MacCallum Cancer Centre (Australia) and the University of Aarhus (Denmark). We acknowledge the National Breast Cancer Foundation (Australia), the Cancer Council of Victoria, the Victorian Cancer Agency and the US Department of Defense for funding epigenetics projects which led directly to the consideration of the issues discussed in this manuscript. Views and opinions of and endorsements by the authors do not reflect those of the US Army or the US Department of Defense. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.