Journal article

Structural insights into the degradation of Mcl-1 induced by BH3 domains

Peter E Czabotar, Erinna F Lee, Mark F van Delft, Catherine L Day, Brian J Smith, David CS Huang, W Douglas Fairlie, Mark G Hinds, Peter M Colman

Proceedings of the National Academy of Sciences | NATL ACAD SCIENCES | Published : 2007

DOI: 10.1073/pnas.0701297104

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Awarded by NCI NIH HHS

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Keywords

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Science & Technology - Other Topics
Survival
Bcl-2 Family
Bh3-Only Proteins
Science & Technology
Myeloid Cell Leukemia Sequence 1 Protein
Amino Acid Sequence
Multiprotein Complexes
Molecular Sequence Data
Nuclear Magnetic Resonance, Biomolecular
Complex
Humans
Multidisciplinary Sciences
Proto-Oncogene Proteins
Recombinant Fusion Proteins
Protein Structure, Tertiary
Mice
Crystallography
Apoptosis Regulatory Proteins
Bim
Noxa
Inhibitor
Proto-Oncogene Proteins C-Bcl-2
Programmed Cell-Death
Differentiation
Neoplasm Proteins
Models, Molecular
Apoptosis
Bcl-2-Like Protein 11
Maximum-Likelihood
Animals
Membrane Proteins