Journal article

Rapid determination of lymphogranuloma venereum serovars of Chlamydia trachomatis by quantitative High-Resolution Melt Analysis (HRMA)

J Twin, MP Stevens, SM Garland, AM Zaia, SN Tabrizi

Journal of Clinical Microbiology | AMER SOC MICROBIOLOGY | Published : 2012

Abstract

A quantitative high-resolution melt analysis assay was developed to differentiate lymphogranuloma venereum-causing serovars of Chlamydia trachomatis (L1 to L3) from other C. trachomatis serovars (D to K). The detection limit of this assay is approximately 10 copies per reaction, comparable to the limits of other quantitative-PCR-based methods. Copyright © 2012, American Society for Microbiology. All Rights Reserved.

University of Melbourne Researchers