Journal article

Associations among smoking status, lifestyle and Lipoprotein subclasses

Alison Beauchamp, Andrew Tonkin, Anna Peeters, Rory Wolfe, Gavin Turrell, Linton Harriss, Graham G Giles, Dallas R English, Alicia J Jenkins

Journal of Clinical Lipidology | ELSEVIER SCIENCE INC | Published : 2010


BACKGROUND: The relationship between cigarette smoking and cardiovascular disease is well established, yet the underlying mechanisms remain unclear. Although smokers have a more atherogenic lipid profile, this may be mediated by other lifestyle-related factors. Analysis of lipoprotein subclasses by the use of nuclear magnetic resonance spectroscopy (NMR) may improve characterisation of lipoprotein abnormalities. OBJECTIVE: We used NMR spectroscopy to investigate the relationships between smoking status, lifestyle-related risk factors, and lipoproteins in a contemporary cohort. METHODS: A total of 612 participants (360 women) aged 40-69 years at baseline (1990-1994) enrolled in the Melbourne ..

View full abstract


Awarded by National Health and Medical Research Council

Funding Acknowledgements

Grants were received from VicHealth, The Cancer Council Victoria, the National Health and Medical Research Council (ID No. 209057 and 334032), and Monash University. A.B. and G.T. are NHMRC funded (ID 465352 and 390109, respectively). A.P. is funded by a VicHealth Fellowship.